This document addresses fluorescence in situ hybridization methods for medical genetic determinations, identification of chromosomal abnormalities, and gene amplification. Recommendations for probe and assay development, manufacture, qualification, verification, and validation; instrument requirements; quality assurance; and evaluation of results are also included.
CLSI MM07-A2 (R2018)
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Fluorescence In Situ Hybridization Methods for Clinical Laboratories; Approved Guideline–Second Edition, MM07A2E
Clinical and Laboratory Standards Institute , 08/30/2013
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