CLSI H59-A (R2018)

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Quantitative D-dimer for the Exclusion of Venous Thromboembolic Disease; Proposed Guideline, H59AE

Clinical and Laboratory Standards Institute , 03/01/2011

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This document provides guidelines regarding the use of D-dimer in exclusion of venous thromboembolism (VTE) including a description of the value of clinical determination of the pretest probability of VTE; the proper collection and handling of the specimen; assays used for D-dimer analysis; determination of the threshold for exclusion of VTE; interpretation of test results; and aspects of regulatory and accreditation requirements.